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Joshi, Arun B.
- Antimicrobial Investigation of Different Extracts of Dolichos lablab Beans
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Authors
Affiliations
1 Dept. of Pharma. Chemistry, B. Pharmacy College, Rampura, Kakanpur, Godhara, Gujarat, IN
2 N.G.S.M Institute of Pharm.Sciences, Paneer, Dearalaktte, Mangalore, IN
3 Pharmacy College, Rampura, Kakanpur, Godhara, Panchmahal, Gujarat, IN
1 Dept. of Pharma. Chemistry, B. Pharmacy College, Rampura, Kakanpur, Godhara, Gujarat, IN
2 N.G.S.M Institute of Pharm.Sciences, Paneer, Dearalaktte, Mangalore, IN
3 Pharmacy College, Rampura, Kakanpur, Godhara, Panchmahal, Gujarat, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 1, No 2 (2009), Pagination: 123-125Abstract
Increasing prevalence of multidrug resistant strains of microorganisms has initiated the exploration of alternate antimicrobial agent. Taking into account the medicinal importance of Dolichos Lablab (Fabaceae) in this respect, an attempt was made in the current study to investigate the antimicrobial potential of this plant. Antimicrobial activity of the ethanolic, petroleum ether, aqueous, chloroform, ethyl acetate and nhexane extracts of Dolichos Lablab beans were determined against various pathogenic bacteria and fungi. The extracts were tested against various bacteria like Bacillus subtilis, Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and fungi like Candida albicans by disk diffusion method. Minimum Inhibitory Concentration (MIC) values of each active extract were determined. It is concluded that n-Hexane and chloroform extract exhibited significant antimicrobial and antifungal activity.Keywords
Dolichos Lablab, Antibacterial, Antifungal, Disk Diffusion Method.- α-Amyrin Caprylate-A New Triterpene Isolated From the Leaf of Bauhinia purpurea linn
Abstract Views :414 |
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Authors
Affiliations
1 Department of Pharmaceutical Chemistry, NGSMIPS, Mangalore, IN
1 Department of Pharmaceutical Chemistry, NGSMIPS, Mangalore, IN
Source
Asian Journal of Research in Chemistry, Vol 2, No 4 (2009), Pagination: 569-570Abstract
Bauhinia purpurea, a useful medicinal plant was subjected to phytochemical investigation. A new ursane triterpenes α-amyrin caprylate (compound 1) was isolated along with other triterpenoids from petroleum ether fraction of ethanolic extract (95%) of leaf of Bauhinia purpurea. Their structures were elucidated with the help of physico-chemical methods and spectroscopic techniques. All of these triterpenes from this plant are being reported for the first time.Keywords
Fabaceae, α-Amyrin Caprylate, Triterpenes.- Antihyperglycemic Activity of Anacardium occidentale (Linn.) in Alloxan Induced Diabetic Rats
Abstract Views :169 |
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Authors
Affiliations
1 Dept. of Pharmacognosy, N.G.S.M Institute of Pharmaceutical Sciences, Paneer, Deralakatte, Mangalore-574160, IN
1 Dept. of Pharmacognosy, N.G.S.M Institute of Pharmaceutical Sciences, Paneer, Deralakatte, Mangalore-574160, IN
Source
Asian Journal of Research in Chemistry, Vol 2, No 3 (2009), Pagination: 262-265Abstract
The investigation was carried out to study the antihyperglycemic effects of ethanolic extract of Anacardium occidentale leaves in normal, glucose loaded and alloxan induced diabetic rats. The ethanolic extract of A. occidentale at a dose of 100, 200, 400 mg/kg of body weight (p.o) and standard drug glibenclamide 500 μg/kg, in all three animal models. The serum glucose level was determined at 0, 4, 8 and 12 days after treatment. The extract exhibited significant hypoglycemic activity in all three animal models when compared with a standard antidiabetic agent Glibenclamide. The hypoglycemia produced by the extract may be due to increased uptake of glucose at tissue level and or increase in pancreatic β-cell function or due to inhibition of intestinal glucose absorption of glucose. The study indicated that the ethanolic extract of Anacardium occidentale is a potential antidiabetic agent and lends scientific support for it’s use in folk medicine.Keywords
Anacardium occidentale, Diaebetes, Alloxan.- Fatty Acids from Memecylon umbellatum (Burm.)
Abstract Views :133 |
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Authors
Himanshu Joshi
1,
Arun B. Joshi
1,
Hemlata Sati
2,
M. P. Gururaja
1,
Prajwal R. Shetty
1,
E. V. S. Subrahmanyam
1,
D. Satyanaryana
1
Affiliations
1 Dept. of Pharma. Chem., NGSM Institute of Pharmaceutical Sciences, Paneer, Deralakatte, Mangalore –574160, IN
2 Department of Pharmacy, H.N.B Garhwal University, Srinagar Garhwal, Uttaranchal, IN
1 Dept. of Pharma. Chem., NGSM Institute of Pharmaceutical Sciences, Paneer, Deralakatte, Mangalore –574160, IN
2 Department of Pharmacy, H.N.B Garhwal University, Srinagar Garhwal, Uttaranchal, IN